Generic drugs are not exactly like brand names

Gianna at Bipolar Blast stumbled upon an article at the LA Times that outlines the FDA’s standard for generics:

In almost all cases, the FDA permits a generic drug to release 80% to
125% of an active ingredient into the bloodstream, compared to that
released in a single dose of the original medication.

Gianna makes a good point for tapering down on brand-name meds then switching to generics:

And definately too broad when I’ve been cutting down my only 10% at a
time. If the drug is 80% of what I’m taking that is a 20% cut without
intending a reduction. It of course can work the other way and make
coming off the drug a longer task and more difficult if it’s actually
125% of the brand name.

eek – that’s something to think about.

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2 Comments

  1. March 19, 2008 at 3:54 pm

    Also, if you are taking the generic for Zoloft…please please please check with your doctor as there was a recall recently regarding certain batches.

  2. Matt said,

    March 28, 2008 at 4:58 pm

    Has anybody had a negative experience with generic drugs? I’m looking to speak with a Minnesota patient who has been switched from a brand name drug to a generic and who could share their experience. If you are interested, please email me at mdepoint@tunheim.com.


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