After a hectic week between work and excessive blogging, I've finally caught up to the latest NYTimes articles on Eli Lilly's troubles with Zyprexa. I also read the NYT's editorial on the issue. The last paragraph caught my eye:
"Lilly contends that it has never promoted Zyprexa for unapproved uses and has always shown its marketing materials to the Food and Drug Administration, as required by law. Both claims ought to be tested in Congressional hearings that should focus on how well the industry complies with existing laws and how effectively the F.D.A. regulates the industry’s marketing materials."
Furious Seasons and CL Psych beat me to the punch on the skepticism. Congressional hearings would do nothing and I am even more skeptical of the FDA. Pharma companies like Lilly probably slip Dr. Andrew C. von Eschenbach some money to get their stuff approved. But I'm merely speculating because I'm tired and haven't done more research on this at the moment.
Continue reading “Catching up…”
While the court is ordering the lawyer who released internal Eli Lilly docuemnts to hand them back, the New York Times is plunging ahead with more shocking revelations concerning the documents. God bless The New York Times and Alex Berenson for taking this story, running with it, and making it public. Even if the company documents become confidential, the story is out and people WILL sue in an attempt to make it public. Patients have a right to know what is affecting their bodies and why Zyprexa causes more medical complications than it helps overcome mental illness.
And God bless Furious Seasons. I don't have time to blog on it, but he does. Head over there to read his critical analysis on the whole situation.
More than likely, I’ll be doing short, quick updates today since I have a LOT of work to get to… you know, at work.
I found a new forum that discusses drug-related items, mainly Paxil: http://www.paxilprogress.org/forums/ It uses one of my more favored layout of forum versions, vBulletin. But they have a worthwhile discussion on the whole Eli Lilly/Zyprexa thing going so it’s worth checking out.
According to the Toronto Sun, Sienna Miller told the UK Mail that she went to a psychiatrist to deal with Jude Law cheating on her — but ended up insulting her when the psych asked a difficult question. Therapy won’t work, dear, if you don’t put any effort into it.
More later on goodies like Christians and depression (what Liz Spikol linked to) and Time‘s Person of the Year. (Okay, Time has NOTHING to with depression but it’s sooo lame it requires a post/rant.)
BTW – I’ll get to everyone’s comments soon. I’m having e-mail issues and once I get them sorted out, I’ll start responding.
Eli Lilly’s actions continue to be appalling.
Apart from trying to hide the fact that Zyprexa induces weight gain, diabetes, and hyperglycemia, they also had sales reps encourage primary care physicians to prescribe Zyprexa for patients who did not have schizophrenia or bipolar disorder (basically off-label usage).
It seems that Lilly told marketing reps to suggest Zyprexa for dementia in the elderly. Lilly denies this, of course, since olanzapine (Zyprexa’s generic name) is not approved for that kind of use since it increases the risk of death in seniors with psychosis associated with dementia. Lilly also attempted to market olanzapine to patients with mild bipolar disorder who suffer mainly from depression. (In actuality, Zyprexa is approved to treat those who suffer from mania.)
This issue with Eli Lilly delves into precisely why I am against PCPs prescribing psychiatric medicines. Primary care physicians don’t know enough about the various psychiatric conditions to prescribe the appropriate kind of medication. This type of prescription should be left to specialists like psychiatrists. PCPs should focus on the things they deal with on a daily basis that no one else can take care of: the common cold, the flu, annual physical, etc. It should be the job of the PCP to refer a patient to a psychiatrist should they present symptoms of mental illness (depression, schizophrenia, etc.). I have been burned by having a PCP prescribe antidepressants for me and as a result, attributed my horrible experience with drugs to that.
Continue reading “PCPs Don't Know Jack From Zyprexa”
Canada.com reports that a Canadian mental health survey found that more than 75 percent of people diagnosed with clinical anxiety or depression experience a severe relapse during the winter months, namely December and January.
“Among the symptoms those people reported, more than half said they experienced ‘feelings of worthlessness,’ ‘inappropriate guilt’ and difficulty thinking or concentrating during the winter holiday season.”
The survey also found that decreased daylight hours and increased debt during the holiday season contribute to stress among those with chronic mental illness. At least the article didn’t say there was a spike in suicides…
Lorraine Bracco, known as Dr. Melfi on The Sopranos, has written a book about her struggle with clinical depression. She notes the difference between how she functioned before her depression hit and after. She cites Zoloft as the antidepressant that helped her overcome the hump and a mental realization that she needed to get help. She no longer uses antidepressants but she feels that the antidepressant got her to a place where she could find herself again, “I found my joie de vivre, my spirit, my voice.”
And finally, it’s time to be pissed off at Eli Lilly. Documents obtained by a mental health lawyer, given to The New York Times, show that Lilly execs tried to downplay the risk of obesity and hyperglycemia in Zyprexa. The two side effects can lead to a significantly increased risk for diabetes. Lilly material even included statements to sales reps telling them to downplay those risks when pitching the atypical antipsychotic to doctors. Zyprexa, Lilly’s best-selling drug, has been sold to 2 million people and has raked in $4.2 billion worldwide. The drug is primarily prescribed for schizophrenia and bipolar disorder. Of course, Lilly execs, aware that the side effects would keep patients away from the drug, downplayed the risks and even went so far as to say, “There is no scientific evidence establishing that Zyprexa causes diabetes.”
Lawsuits speaks differently, however. Lilly has agreed to pay $750 million to 8,000 people who claim that Zyprexa has caused them to develop diabetes or other medical problems. According to the Times, “thousands more suits against the company are pending.”
Continue reading “Loose Screws Mental Health News”