An inhalation drug for schizophrenia and bipolar disorder???

Oh no they didn’t. From Alexza Pharmaceuticals’ recent PR:

Staccato system-inhalationAlexza Pharmaceuticals, Inc. announced today that it has initiated its second Phase 3 clinical trial with AZ-004 (Staccato(R) loxapine). AZ-004 is an inhalation product candidate being developed for the treatment of acute agitation in patients with schizophrenia or bipolar disorder. Alexza believes the novel, non-invasive nature and rapid pharmacokinetic (PK) properties resulting from inhaled loxapine administration via the Staccato system (click on the photo to the right to see an enlargelarement) have the potential to make AZ-004 a viable product to treat acute agitation.

The supposed benefits:

  1. Rapid onset
  2. Ease of use
  3. Consistent dose and particle size
  4. Broad applicability

Is this pharmaceutical company really developing a product to treat schizophrenic and bipolar disorder symptoms by inhaling? I thought the injectable Risperdal was bad. Check out how the Staccato system works. It blows my mind that psych drugs are being developed for injection and inhalation.

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10 Comments

  1. Naturalgal said,

    July 29, 2008 at 9:10 am

    My cousin wears an antidepressant patch.

  2. Marissa said,

    July 29, 2008 at 10:15 am

    Hm. I’ve never heard of antidepressant patch.

  3. Jazz said,

    July 29, 2008 at 10:17 am

    And this surprises us, why?

  4. Marissa said,

    July 29, 2008 at 10:40 am

    I’m waiting for the enema version of an antipsychotic.

  5. Naturalgal said,

    July 29, 2008 at 11:21 am

    EWWW!!
    Then they can really stick it to ya.

  6. Stephany said,

    July 29, 2008 at 3:49 pm

    Oh brother! though I can imagine psych wards wanting a air system version so the entire unit will be drugged, while they teach yoga and deep breathing techniques!
    It reminds me of one summer my daughter was suffering from a psychotic event, and I took her to an “oxygen bar” where we sat and listened music (it was in a clothes boutique)and had the oxygen tubes under our noses, then the person told us to go eat chocolate and all would feel better.
    Serious. Guess what? it didnt work, either will this drug!

  7. Marissa said,

    July 29, 2008 at 4:33 pm

    Ack! Oxygen bar?? Chocolate??
    Stephany, the things that people come up with should cease to surprise me but they never do. I’m losing hope in humanity.

  8. Stephany said,

    July 30, 2008 at 1:11 pm

    Yes that was actually a pretty funny day, I should write about it!

  9. Jessie said,

    August 4, 2008 at 5:01 am

    What’s wrong with this picture? I think it looks like a pretty concept…easier than popping a pill. But LOL & Naturalgal, the airsystem idea sounds effective.

  10. lilstarrr said,

    August 13, 2008 at 4:14 pm

    you know when my brother eats chocalate he usually has a psychotic episode as a result.


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