Chemical imbalances do not exist; dying brain cells do

Researchers have never been fully confident in the chemical imbalance theory, yet the media continue to purport it as fact. Dr. John Grohol over at PsychCentral recently wrote:

We’ve all heard the theory — a chemical imbalance in your brain causes depression.

Although researchers have known for years this not to be the case, some drug companies continue to repeat this simplistic and misleading claim in their marketing and advertising materials. Why the FTC or some other federal agency doesn’t crack down on this intentional misleading information is beyond me. Most researchers now believe depression is not caused by a chemical imbalance in the brain.

How did we come to this conclusion? Through years of additional research. But now some are jumping on the next brain bandwagon of belief — that depression is caused by a problem in the brain neuronal network.

Grohol cites Jonah Lehrer's article in the Boston Globe in which he posits that researchers now think depression comes from "brain cells shrinking and dying." Lehrer writes:

Continue reading “Chemical imbalances do not exist; dying brain cells do”

Celebrity Sensitivity: Juliana Hatfield & George Michael

Juliana HatfieldJuliana Hatfield, a singer who enjoyed great success in the 1990s, expressed frustration with the PR machine that covered up her bout with severe depression. So severe that she canceled a European tour. Her publicist spread word that she was suffering from “nervous exhaustion.” However, Hatfield reveals:

[My depression was] so unbearable that I was going to jump out of a window to get away from it . . . I needed to check myself into some kind of psychiatric-treatment facility.

I wondered why my publicist hadn’t simply told everyone the plain truth . . . instead of issuing such a vague, all-purpose ‘nervous exhaustion’ line, which . . . as far as I know isn’t even a real diagnosis.

Hatfield, who has an album due out in mid-August, appears to have sacrificed long-term mainstream success in exchange for her mental well-being. Given the choice she had to make, I’m sure she couldn’t be happier.

(Hat tip: Powerline A.D.)

On another note, George Michael (who is currently on tour) recently divulged his 20-year battle with depression on Good Morning America. He attributed his music to helping him cope with such events as the deaths of his boyfriend and his mother.

CCEF 2008 Annual Conference: The Addict In Us All

CCEF 2008 Annual Conference

I’ve previously mentioned that I receive (currently weekly) counseling at CCEF in Glenside, PA. They hold a conference every year on various topics. Last year’s subject was overcoming fear and my husband and I found it to be immensely helpful. This year’s topic focuses on addiction. I received a PR from them and am posting it below.


Christian Counseling & Educational Foundation (CCEF) Announces
2008 Annual Conference – The Addict in Us All

Addiction sounds ominous, and it is. Addictions to drugs, alcohol, and gambling tear families apart and ruin lives. But this conference is about more than the junkie scoring dope or the alcoholic hiding vodka around the house. Even the average person gets stuck in negative behavior patterns. Overeating, shopping, sexual temptation, people’s approval, even love…everyone struggles with something. And everyone faces moments of despair and thinking that change is not possible.

Continue reading “CCEF 2008 Annual Conference: The Addict In Us All”

Leaving comments

A few days ago, I was a whiny little 12-year-old asking for people to leave more comments.

Ignore that. It was a stupid attempt to inflate my little ego.

What really matters is that people read some of these posts and find the information helpful. I’d prefer that people walk away from this blog empowered with knowledge rather than just feeling obligated to leave comments.

Naturalgal mentioned that she’s turned off by CAPTCHA. I don’t blame her. I have pretty good eyesight and it’s frustrating for me as well. I’m hesitant to turn it off because my spam filter has caught 301 spam posts in the past 30 days. I don’t have time to sift legitimate comments from a plethora of others that contain words like p***y, d**k, and c**t.

You get the idea.

Leave comments if you wish, but don’t feel the need to do so because I said so.  Forgive me for my moment of selfishness.

A thought on Mad Pride

Maybe I’ve got the whole Mad Pride thing all wrong but I’m not proud of anything I’m dealing with. I just hope I can share my experience and knowledge to help others. Perhaps Mad Pride means being proud to be an activist on this issue?

An inhalation drug for schizophrenia and bipolar disorder???

Oh no they didn’t. From Alexza Pharmaceuticals’ recent PR:

Staccato system-inhalationAlexza Pharmaceuticals, Inc. announced today that it has initiated its second Phase 3 clinical trial with AZ-004 (Staccato(R) loxapine). AZ-004 is an inhalation product candidate being developed for the treatment of acute agitation in patients with schizophrenia or bipolar disorder. Alexza believes the novel, non-invasive nature and rapid pharmacokinetic (PK) properties resulting from inhaled loxapine administration via the Staccato system (click on the photo to the right to see an enlargelarement) have the potential to make AZ-004 a viable product to treat acute agitation.

The supposed benefits:

  1. Rapid onset
  2. Ease of use
  3. Consistent dose and particle size
  4. Broad applicability

Is this pharmaceutical company really developing a product to treat schizophrenic and bipolar disorder symptoms by inhaling? I thought the injectable Risperdal was bad. Check out how the Staccato system works. It blows my mind that psych drugs are being developed for injection and inhalation.

Pristiq's side effects: Too close to Premarin and Prempro for comfort?

Back in January 2007, I’d mentioned that Wyeth was not only seeking to market Pristiq (desvenlafaxine) for depression but also for the use of vasomotor symptoms in menopausal women.

I just learned that Wyeth produces two major menopause drugs, Premarin and Prempro, that allegedly has produced hormones causing cancer in more than 5,000 women. This added up to a loss of 40 million users and $1 billion annually.

With Effexor going generic in 2 years and the introduction of Pristiq to the market, Wyeth hopes to lure some of those customers back and net an annual $2 billion. However, serious questions linger about Pristiq’s side effects in menopausal women.

Why did two women in the study group taking Pristiq have heart attacks
and three need procedures to repair clogged arteries compared with none
taking placebo? How can Wyeth assure long term safety when 604 of the
2,158 test subjects took Pristiq for only six months and 318 for a year
or more? And what about serious liver complications seen in the studies?

Martha Rosenberg, reporting on Pristiq’s use as a menopausal drug, culled comments from CafePharma’s message boards and found one thread rife with mixed comments on the new drug. From an Anonymous commenter:

Continue reading “Pristiq's side effects: Too close to Premarin and Prempro for comfort?”

More Famous People With Mental Illness

The local NAMI chapter has literature all over a counter at my local library. One of the pieces of literature actually was a 5×7 index card with a list of famous people who struggled with mental illness. It was kind of interesting so I figured I’d share it. Some I’d already known about; others were a bit of a surprise. How did they figure out who had bipolar disorder back in the 1800s?

Continue reading “More Famous People With Mental Illness”

Pick a number: 20 or 9,000,000

20 people annually or 9,000,000 people annually.

Golden Gate BridgeThose are the numbers that the Golden Gate Bridge (GGB) Board of Directors will need to choose between in October.

GGB officials are considering a proposal to erect suicide barriers on the bridge. Public forums were held on Tuesday and Wednesday to gauge public reaction to the five options designed to deter suicides. The cost of erecting one of the barriers is estimated between $40–50 million.

Bridge officials have been culling comments about the barriers at the forums and through the site Golden Gate Bridge Suicide Deterrent Barrier. As of Wednesday, July 23, the San Francisco Chronicle reports:

[O]f the more than 900 tallied so far, an overwhelming 75 percent of the respondents said they prefer that no barrier be built at all. But a small, passionate group of proponents – many of them family
members of people who jumped to their deaths from the bridge – insist a barrier is needed. Any barrier.

“Overwhelming 75 percent” prefer no barrier? That’s not good.

Opponents of the barriers say it will ruin the aesthetic view of the bridge for the yearly estimated 9 million visitors.

I stumbled upon a blog, Bookworm Room, yesterday that brought the issue to my attention. This blogger likely represents the sentiment of the “overwhelming 75 percent.”

Continue reading “Pick a number: 20 or 9,000,000”